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Chloride Voltage-Gated Channel 7 (CLCN7) Antibody
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Catalogue No: abx005242
Price:
US$217.50
(Size: 20 µl)
Orders to United States ship from United States
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CLCN7 Antibody is a Rabbit Polyclonal antibody against CLCN7. The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.
Research Articles on Chloride Voltage-Gated Channel 7 (CLCN7)
| Target | Chloride Voltage-Gated Channel 7 (CLCN7) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 626-805 of human CLCN7. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P51798 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NEJ7, A8K5T9, A8K7X1, B3KPN3, E9PDB9, Q9NYX5 |
| UniProt Entry Name | CLCN7_HUMAN |
| Gene Symbol | CLCN7 |
| GeneID | 1186 |
| NCBI Accession | NP_001278.1 |
| KEGG | hsa:1186 |
| String | 9606.ENSP00000372193 |
| Molecular Weight | Calculated MW: 89 kDa Observed MW: 110 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |