Chloride Voltage-Gated Channel Kb (CLCNKB) Antibody

The protein encoded by this gene is a member of the family of voltage-gated chloride channels. Chloride channels have several functions, including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. This gene is expressed predominantly in the kidney and may be important for renal salt reabsorption. Mutations in this gene are associated with autosomal recessive Bartter syndrome type 3 (BS3). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Target	Chloride Voltage-Gated Channel Kb (CLCNKB)
Clonality	Polyclonal
Reactivity	Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 11-40 amino acids from the N-terminal region of human CLCNKB.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P51801 (UniProt, ExPASy)
UniProt Secondary AC	B3KUY3, Q5T5Q7, Q5T5Q8
UniProt Entry Name	CLCKB_HUMAN
KEGG	hsa:1188
String	9606.ENSP00000364831
Molecular Weight	Calculated MW: 75.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Chloride Voltage-Gated Channel Kb (CLCNKB)

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