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Claudin 7 (CLDN7) Antibody
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Catalogue No: abx001652
Price:
US$203.00
(Size: 20 µl)
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CLDN7 Antibody is a Rabbit Polyclonal antibody against CLDN7. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010].
Research Articles on Claudin 7 (CLDN7)
| Target | Claudin 7 (CLDN7) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000 - 1/5000, IF/ICC: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 29-211 of human CLDN7. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O95471 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R9X7, D3DTP0, Q6IPN3, Q7Z4Y7, Q9BVN0 |
| UniProt Entry Name | CLD7_HUMAN |
| Gene Symbol | CLDN7 |
| GeneID | 1366 |
| NCBI Accession | NP_001298.3 |
| KEGG | hsa:1366 |
| String | 9606.ENSP00000353475 |
| Molecular Weight | Calculated MW: 22 kDa Observed MW: 22 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |