Dual Specificity Protein Kinase CLK2 (CLK2) Antibody

This gene encodes a member of the CLK family of dual specificity protein kinases. CLK family members have shown to interact with, and phosphorylate, serine and arginine-rich (SR) proteins of the spliceosomal complex, which is a part of the regulatory mechanism that enables the SR proteins to control RNA splicing. This protein kinase is involved in the regulation of several cellular processes and may serve as a link between cell cycle progression, apoptosis, and telomere length regulation.

Target	Dual Specificity Protein Kinase CLK2 (CLK2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CLK2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P49760 (UniProt, ExPASy)
UniProt Secondary AC	B1AVS9, B5MBX6, Q96CQ0
UniProt Entry Name	CLK2_HUMAN
Gene Symbol	CLK2
GeneID	1196
OMIM	602989
NCBI Accession	NP_003984.2
HGNC	2069
KEGG	hsa:1196
Ensembl	ENSG00000176444
String	9606.ENSP00000357345
Molecular Weight	Calculated MW: 60.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse CLK2.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Dual Specificity Protein Kinase CLK2 (CLK2)

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