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Cannabinoid Receptor 1, Brain / CB1 (CNR1) Antibody
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Catalogue No: abx001241
Price:
US$203.00
(Size: 20 µl)
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Cannabinoid Receptor 1, Brain / CB1 (CNR1) Antibody is a Rabbit Polyclonal antibody against CNR1. This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009].
Research Articles on Cannabinoid Receptor 1, Brain / CB1 (CNR1)
| Target | Cannabinoid Receptor 1, Brain / CB1 (CNR1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 401-472 of human CNR1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P21554 (UniProt, ExPASy) |
| UniProt Entry Name | CNR1_HUMAN |
| Gene Symbol | CNR1 |
| GeneID | 1268 |
| OMIM | 114610 |
| NCBI Accession | NP_001153698.1 |
| HGNC | 2159 |
| KEGG | hsa:1268 |
| Ensembl | ENSG00000118432 |
| String | 9606.ENSP00000358513 |
| Molecular Weight | Calculated MW: 53 kDa Observed MW: 60 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 1.218 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |