Coilin (COIL) Antibody

COIL Antibody is a Rabbit Polyclonal antibody against COIL. The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.

Target	Coilin (COIL)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IP: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 297-576 of human Coilin.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P38432 (UniProt, ExPASy)
UniProt Secondary AC	B2R931
UniProt Entry Name	COIL_HUMAN
Gene Symbol	COIL
GeneID	8161
NCBI Accession	NP_004636.1
KEGG	hsa:8161
String	9606.ENSP00000240316
Molecular Weight	Calculated MW: 63 kDa Observed MW: 80 kDa
Buffer	PBS, pH 7.3, containing 0.09% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Coilin (COIL)

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