Collagen Type VI Alpha 1 (COL6A1) Antibody

The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1 (VI), alpha2 (VI), and alpha3 (VI) chains. The protein COL6A1 is the alpha 1 subunit of type VI collagen (alpha1 (VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.

Target	Collagen Type VI Alpha 1 (COL6A1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 48-77 amino acids from the N-terminal region of human COL6A1.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P12109 (UniProt, ExPASy)
UniProt Secondary AC	O00117, O00118, Q14040, Q14041, Q16258, Q7Z645, Q9BSA8
UniProt Entry Name	CO6A1_HUMAN
KEGG	hsa:1291
String	9606.ENSP00000355180
Molecular Weight	Calculated MW: 109 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse COL6A1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Collagen Type VI Alpha 1 (COL6A1)

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