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Complement C3 (C3) Antibody
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Catalogue No: abx109668
Price:
US$188.50
(Size: 20 µg)
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Complement C3 (C3) Antibody is a Rabbit Polyclonal antibody against Complement C3. C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
Research Articles on Complement C3 (C3)
| Target | Complement C3 (C3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IHC: 1/50 - 1/500, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant human Complement C3 protein (26-225AA). |
| Isotype | IgG |
| Form | Liquid |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P01024 (UniProt, ExPASy) |
| UniProt Secondary AC | A7E236 |
| UniProt Entry Name | CO3_HUMAN |
| Gene Symbol | C3 |
| GeneID | 718 |
| OMIM | 120700 |
| HGNC | 1318 |
| KEGG | hsa:718 |
| Ensembl | ENSG00000125730 |
| String | 9606.ENSP00000245907 |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |