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COP9 Constitutive Photomorphogenic Homolog Subunit 6 (COPS6) Antibody
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Catalogue No: abx005350
Price:
US$217.50
(Size: 20 µl)
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COPS6 Antibody is a Rabbit Polyclonal antibody against COPS6. The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.
Research Articles on COP9 Constitutive Photomorphogenic Homolog Subunit 6 (COPS6)
| Target | COP9 Constitutive Photomorphogenic Homolog Subunit 6 (COPS6) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/100 - 1/500, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 58-327 of human COPS6. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q7L5N1 (UniProt, ExPASy) |
| UniProt Secondary AC | A4D2A3, O15387 |
| UniProt Entry Name | CSN6_HUMAN |
| Gene Symbol | COPS6 |
| GeneID | 10980 |
| NCBI Accession | NP_006824.2 |
| KEGG | hsa:10980 |
| String | 9606.ENSP00000304102 |
| Molecular Weight | Calculated MW: 36 kDa Observed MW: 35 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |