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Coatomer Protein Complex Subunit Zeta 1 (COPZ1) Antibody
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Catalogue No: abx027226
Price:
US$290.00
(Size: 80 µl)
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The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity). The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
Research Articles on Coatomer Protein Complex Subunit Zeta 1 (COPZ1)
| Target | Coatomer Protein Complex Subunit Zeta 1 (COPZ1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 24-53 amino acids from the N-terminal region of human COPZ1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P61923 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DDX8, B4DHZ0, F8VS17, F8VWL5, Q549N6, Q9Y3C3 |
| UniProt Entry Name | COPZ1_HUMAN |
| KEGG | hsa:22818 |
| String | 9606.ENSP00000449270 |
| Molecular Weight | Calculated MW: 20.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Cow COPZ1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |