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Cortactin (CTTN) Antibody
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Catalogue No: abx025373
Price:
US$623.50
(Size: 100 µl)
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This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. This antibody is supplied as crude ascites.
Research Articles on Cortactin (CTTN)
| Target | Cortactin (CTTN) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/1000 - 1/8000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified His-tagged Human Cortactin protein (Fragment) |
| Isotype | IgM |
| Form | Liquid |
| Purification | Unpurified crude ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q14247 (UniProt, ExPASy) |
| UniProt Secondary AC | Q8N707, Q96H99 |
| UniProt Entry Name | SRC8_HUMAN |
| KEGG | hsa:2017 |
| Molecular Weight | Calculated MW: 61.6 kDa |
| Buffer | Ascites containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |