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Introduction | Rotaviruses are dsRNA viruses that infect humans and livestock. Infection is mediated via contact with contaminated matter, and transmitted via the fecal-oral route. The virus replicates predominantly in intestinal enterocytes and enterochromaffin cells, causing their destruction. Additionally, the virus induces chloride secretion into the lumen, causing diarrhoea, and the infected enterochromaffin cells release serotonin, causing nausea and vomiting. The infection is typically cleared in approximately 1 week, with minimal risk if enough fluids and electrolytes are available to the patient (which is not always achievable in developing regions). Vaccines against the pathogen are available and have been linked to a reduced incidence of type I diabetes. |
Target | Rotavirus IgM (RV IgM) |
Reactivity | Cow |
Tested Applications | ELISA |
Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Validity | The validity for this kit is 6 months. |
Stability | The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Assay Type | Indirect |
Assay Data | Qualitative |
Sample Type | Serum and plasma. |
Availability | Shipped within 5-10 working days. |
Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Plate coated with | Antigen |