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Cytochrome C Oxidase Subunit 6A1 (COX6A1) Antibody
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Catalogue No: abx002749
Price:
US$348.00
(Size: 60 µl)
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COX6A1 Antibody is a Rabbit Polyclonal antibody against COX6A1. Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66% amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented.
Research Articles on Cytochrome C Oxidase Subunit 6A1 (COX6A1)
| Target | Cytochrome C Oxidase Subunit 6A1 (COX6A1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/200 - 1/2000, IHC-P: 1/20 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human COX6A1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P12074 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R500, O43714, Q32Q37 |
| UniProt Entry Name | CX6A1_HUMAN |
| Gene Symbol | COX6A1 |
| GeneID | 1337 |
| NCBI Accession | NP_004364.2 |
| KEGG | hsa:1337 |
| String | 9606.ENSP00000229379 |
| Molecular Weight | Calculated MW: 12 kDa Observed MW: 12 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |