Cytochrome C Oxidase Subunit 6B1 (COX6B1) Antibody

Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively.

Target	Cytochrome C Oxidase Subunit 6B1 (COX6B1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 59-86 amino acids from the C-terminal region of human COX6B1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P14854 (UniProt, ExPASy)
UniProt Secondary AC	B2R5C9, Q6IBL4
UniProt Entry Name	CX6B1_HUMAN
KEGG	hsa:1340
String	9606.ENSP00000246554
Molecular Weight	Calculated MW: 10.2 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Monkey COX6B1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cytochrome C Oxidase Subunit 6B1 (COX6B1)

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