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Cytochrome C Oxidase Subunit 7A2 Like (COX7A2L) Antibody
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Catalogue No: abx026739
Price:
US$326.25
(Size: 80 µl)
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Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen.
Research Articles on Cytochrome C Oxidase Subunit 7A2 Like (COX7A2L)
| Target | Cytochrome C Oxidase Subunit 7A2 Like (COX7A2L) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 37-65 amino acids from the Central region of human COX7A2L. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O14548 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9P118 |
| UniProt Entry Name | COX7R_HUMAN |
| Gene Symbol | COX7A2L |
| KEGG | hsa:9167 |
| String | 9606.ENSP00000367938 |
| Molecular Weight | Calculated MW: 12.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |