Carboxypeptidase E (CPE) Antibody

CPE Antibody is a Rabbit Polyclonal antibody against CPE. This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes.

Target	Carboxypeptidase E (CPE)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 257-476 of human CPE.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P16870 (UniProt, ExPASy)
UniProt Secondary AC	A8K4N1, B3KR42, B4DFN4, D3DP33, Q9UIU9
UniProt Entry Name	CBPE_HUMAN
Gene Symbol	CPE
GeneID	1363
NCBI Accession	NP_001864.1
KEGG	hsa:1363
String	9606.ENSP00000386104
Molecular Weight	Calculated MW: 53 kDa Observed MW: 53-55 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Carboxypeptidase E (CPE)

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