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Creatine Kinase B Antibody
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Catalogue No: abx033151
Price:
US$326.25
(Size: 80 µl)
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Creatine Kinase (CK) is a dimeric enzyme composed of either M or B-type subunits. The resulting isoenzymes are expressed at varying levels in different tissues. CK-BB, a cytoplasmic predominantly found in brain tissues, participates in energy homeostasis, reversibly catalyzing the transfer of a phosphate group between ATP and target proteins such as a creatine phosphate. CK-BB exists in normally neglible amounts in the serum of adults, overexpression of CK-BB is associated with cancers of the breast, ovary, prostate, colon, and in small-cell lung cancer. Global assessment of changes in serum levels of CK-BB, CK-MB and CK-MM, are used as a marker for myocardial infarction.
Research Articles on Creatine Kinase B
| Target | Creatine Kinase B |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 240-270 amino acids from the C-terminal region of human Creatine Kinase B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P12277 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K236, B2R5R4, Q2LE07, Q6FG40, Q9UC66 |
| UniProt Entry Name | KCRB_HUMAN |
| NCBI Accession | NP_001814.2 |
| KEGG | hsa:1152 |
| String | 9606.ENSP00000299198 |
| Molecular Weight | Calculated MW: 42.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |