CREB (pS133) Antibody

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Catalogue No: abx031855
Price: US$326.25
(Size: 80 µl)

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Documents

Datasheet SDS
CREB is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, (CRE), a sequence present in many viral and cellular promoters. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway.

Target CREB (pS133)
Clonality Polyclonal
Target Modification Ser133
Modification Phosphorylation
Reactivity Human
Tested Applications ELISA, WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500, IHC-P: 1/500. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S133 of human CREB.
Isotype IgG
Form Liquid
Purification Purified by protein G affinity chromatography. Then, the antibody fraction was peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P16220 (UniProt, ExPASy)
UniProt Secondary AC P21934, Q6V963, Q9UMA7
UniProt Entry Name CREB1_HUMAN
KEGG hsa:1385
String 9606.ENSP00000387699
Molecular Weight Calculated MW: 35.1 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on CREB (pS133)


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