Cyclic AMP-Responsive Element Binding Protein 3 (CREB3) Antibody

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.

Target	Cyclic AMP-Responsive Element Binding Protein 3 (CREB3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human CREB3.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O43889 (UniProt, ExPASy)
UniProt Secondary AC	D0PTW6, O14671, O14919, Q5TCV1, Q96GK8, Q9H2W3, Q9UE77
UniProt Entry Name	CREB3_HUMAN
Gene Symbol	CREB3
KEGG	hsa:10488
String	9606.ENSP00000342136
Molecular Weight	Calculated MW: 41.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cyclic AMP-Responsive Element Binding Protein 3 (CREB3)

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