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Cyclic AMP-Responsive Element Binding Protein 3 (CREB3) Antibody
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Catalogue No: abx005039
Price:
US$348.00
(Size: 60 µl)
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CREB3 Antibody is a Rabbit Polyclonal antibody against CREB3. This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.
Research Articles on Cyclic AMP-Responsive Element Binding Protein 3 (CREB3)
| Target | Cyclic AMP-Responsive Element Binding Protein 3 (CREB3) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IF/ICC: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human CREB3 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O43889 (UniProt, ExPASy) |
| UniProt Secondary AC | D0PTW6, O14671, O14919, Q5TCV1, Q96GK8, Q9H2W3, Q9UE77 |
| UniProt Entry Name | CREB3_HUMAN |
| Gene Symbol | CREB3 |
| GeneID | 10488 |
| NCBI Accession | NP_006359.3 |
| KEGG | hsa:10488 |
| String | 9606.ENSP00000342136 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
