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cAMP-Responsive Element-Binding Protein-Like 1 (CREBL1) Antibody
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Catalogue No: abx032412
Price:
US$326.25
(Size: 80 µl)
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CREBL1 is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus.
Research Articles on cAMP-Responsive Element-Binding Protein-Like 1 (CREBL1)
| Target | cAMP-Responsive Element-Binding Protein-Like 1 (CREBL1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Hamster |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 560-589 amino acids from the C-terminal region of human CREBL1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q99941 (UniProt, ExPASy) |
| UniProt Entry Name | ATF6B_HUMAN |
| Gene Symbol | ATF6B |
| KEGG | hsa:1388 |
| String | 9606.ENSP00000364349 |
| Molecular Weight | Calculated MW: 76.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |