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Crk-Like Protein (CRKL) Antibody
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Catalogue No: abx012058
Price:
US$420.50
(Size: 100 µl)
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This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
Research Articles on Crk-Like Protein (CRKL)
| Target | Crk-Like Protein (CRKL) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human CRKL expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P46109 (UniProt, ExPASy) |
| UniProt Secondary AC | A8KA44, D3DX35 |
| UniProt Entry Name | CRKL_HUMAN |
| Gene Symbol | CRKL |
| GeneID | 1399 |
| OMIM | 602007 |
| HGNC | 2363 |
| KEGG | hsa:1399 |
| Ensembl | ENSG00000099942 |
| String | 9606.ENSP00000346300 |
| Molecular Weight | 39 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |