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Cone-Rod Homeobox (CRX) Antibody
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Catalogue No: abx004373
Price:
US$203.00
(Size: 20 µl)
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CRX Antibody is a Rabbit Polyclonal antibody against CRX. The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
Research Articles on Cone-Rod Homeobox (CRX)
| Target | Cone-Rod Homeobox (CRX) |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CRX. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O43186 (UniProt, ExPASy) |
| UniProt Secondary AC | Q0QD45 |
| UniProt Entry Name | CRX_HUMAN |
| Gene Symbol | CRX |
| GeneID | 1406 |
| OMIM | 120970 |
| NCBI Accession | NP_000545.1 |
| HGNC | 2383 |
| KEGG | hsa:1406 |
| Ensembl | ENSG00000105392 |
| String | 9606.ENSP00000221996 |
| Molecular Weight | Calculated MW: 32 kDa Observed MW: 37 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |