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Macrophage Colony-Stimulating Factor 1 Receptor (CSF1R) Antibody
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Catalogue No: abx002189
Price:
US$203.00
(Size: 20 µl)
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CSF1R Antibody is a Rabbit Polyclonal antibody against CSF1R. The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction.
Research Articles on Macrophage Colony-Stimulating Factor 1 Receptor (CSF1R)
| Target | Macrophage Colony-Stimulating Factor 1 Receptor (CSF1R) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 873-972 of human CD115/CSF-1R. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P07333 (UniProt, ExPASy) |
| UniProt Secondary AC | B5A955, D3DQG2, Q6LDW5, Q6LDY4, Q86VW7 |
| UniProt Entry Name | CSF1R_HUMAN |
| Gene Symbol | CSF1R |
| GeneID | 1436 |
| NCBI Accession | NP_005202.2 |
| KEGG | hsa:1436 |
| String | 9606.ENSP00000286301 |
| Molecular Weight | Calculated MW: 108 kDa Observed MW: 150-190 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |