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Transcriptional Repressor CTCFL (CTCFL) Antibody
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Catalogue No: abx004704
Price:
US$217.50
(Size: 20 µl)
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CTCFL Antibody is a Rabbit Polyclonal antibody against CTCFL. CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Articles on Transcriptional Repressor CTCFL (CTCFL)
| Target | Transcriptional Repressor CTCFL (CTCFL) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CTCFL. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q8NI51 (UniProt, ExPASy) |
| UniProt Entry Name | CTCFL_HUMAN |
| Gene Symbol | CTCFL |
| GeneID | 140690 |
| NCBI Accession | NP_001255970.1 |
| KEGG | hsa:140690 |
| String | 9606.ENSP00000415579 |
| Molecular Weight | Calculated MW: 76 kDa Observed MW: 83 kDa |
| Buffer | PBS, pH 7.3, containing 0.09% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |