CTD Small Phosphatase Like Protein 1 (CTDSP1) Antibody

Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

Target	CTD Small Phosphatase Like Protein 1 (CTDSP1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CTDSP1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9GZU7 (UniProt, ExPASy)
UniProt Secondary AC	C9IYG0, Q7Z5Q3, Q7Z5Q4
UniProt Entry Name	CTDS1_HUMAN
Gene Symbol	CTDSP1
String	9606.ENSP00000273062
Molecular Weight	Calculated MW: 29.2 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse CTDSP1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on CTD Small Phosphatase Like Protein 1 (CTDSP1)

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