C-X-C Motif Chemokine 11 / I-TAC (CXCL11) Antibody

CXCL11 Antibody is a Rabbit Polyclonal antibody against CXCL11. Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene.

Target	C-X-C Motif Chemokine 11 / I-TAC (CXCL11)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	IHC
Host	Rabbit
Recommended dilutions	IHC-P: 1/100 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 22-94 of human CXCL11.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O14625 (UniProt, ExPASy)
UniProt Secondary AC	Q53YA3, Q92840
UniProt Entry Name	CXL11_HUMAN
Gene Symbol	CXCL11
GeneID	6373
NCBI Accession	NP_005400.1
KEGG	hsa:6373
String	9606.ENSP00000306884
Molecular Weight	Calculated MW: 10 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on C-X-C Motif Chemokine 11 / I-TAC (CXCL11)

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