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Chemokine C-X-C-Motif Receptor 3 (CXCR3) Antibody
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Catalogue No: abx002145
Price:
US$203.00
(Size: 20 µl)
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CXCR3 Antibody is a Rabbit Polyclonal antibody against CXCR3. The neuronal growth-associated protein GAP43 is also known as neuromodulin, B-50, P-57, F1 and pp46. Deficiency of GAP43 in mice results in death early in the postnatal period. GAP43 is one of the main substrates for protein kinase C in the brain. GAP43 is an intracellular growth-associated protein that appears to assist neuronal pathfinding and branching during development and regeneration, and may contribute to presynaptic membrane changes in the adult, leading to the neurotransmitter release, endocytosis and synaptic vesicle recycling, long-term potentiation, spatial memory formation, and learning. The predicated molecular weight of about 25 kDa is much lower than the apparent observed molecular weight of 43 kDa on SDS-PAGE gels, and this occurs because the highly charged nature of GAP43 causes it to bind less than the average amount of SDS per amino acid, and because the protein has an elongated structure.
Research Articles on Chemokine C-X-C-Motif Receptor 3 (CXCR3)
| Target | Chemokine C-X-C-Motif Receptor 3 (CXCR3) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 289-368 of human CXCR3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P49682 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R982, O15185, Q7Z710, Q9P2T4, Q9P2T5 |
| UniProt Entry Name | CXCR3_HUMAN |
| Gene Symbol | CXCR3 |
| GeneID | 2833 |
| NCBI Accession | NP_001495.1 |
| KEGG | hsa:2833 |
| String | 9606.ENSP00000362795 |
| Molecular Weight | Calculated MW: 41 kDa Observed MW: 44 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |