Human Anti-Cyclic Citrullinated Peptide Antibody (Anti-CCP) ELISA Kit

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Catalogue No: abx364945
Price: US$572.75
(Size: 96 tests)

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Cyclic Citrullinated Peptide (CCP) Antibody ELISA Kit is an ELISA Kit against Cyclic Citrullinated Peptide (CCP) Antibody.

Introduction Anti-citrullinated protein antibodies (ACPAs) are autoantibodies that are directed against peptides and proteins that are citrullinated. They are present in the majority of patients with rheumatoid arthritis. During inflammation, arginine amino acid residues can be enzymatically converted into citrulline residues in proteins such as vimentin, by a process called citrullination. If their shapes are significantly altered, the proteins may be seen as antigens by the immune system, thereby generating an immune response. ACPAs have proved to be powerful biomarkers that allow the diagnosis of rheumatoid arthritis (RA) to be made at a very early stage.
Target Anti-Cyclic Citrullinated Peptide Antibody (Anti-CCP)
Reactivity Human
Tested Applications ELISA
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Storage Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Validity The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Stability The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.
Standard Form Lyophilized
Detection Method Colorimetric
Assay Type Indirect
Assay Data Qualitative
Sample Type Serum
Availability Shipped within 5-12 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES.

Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Research Articles on Anti-Cyclic Citrullinated Peptide Antibody (Anti-CCP)


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