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Cyclin E2 (CCNE2) Antibody
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Catalogue No: abx149261
Price:
US$406.00
(Size: 100 µg)
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Cyclin E2 (CCNE2) Antibody is a Rabbit Polyclonal antibody for the detection of CCNE2. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells.
Research Articles on Cyclin E2 (CCNE2)
| Target | Cyclin E2 (CCNE2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | G1/S-specific cyclin-E2 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | O96020 (UniProt, ExPASy) |
| UniProt Secondary AC | O95439 |
| UniProt Entry Name | CCNE2_HUMAN |
| Gene Symbol | CCNE2 |
| GeneID | 9134 |
| OMIM | 603775 |
| HGNC | 1590 |
| KEGG | hsa:9134 |
| Ensembl | ENSG00000175305 |
| String | 9606.ENSP00000429089 |
| Molecular Weight | Observed MW: 44 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |