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Steroid 17-Alpha-Hydroxylase/17,20 Lyase (CYP17A1) Antibody
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Catalogue No: abx001208
Price:
US$203.00
(Size: 20 µl)
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CYP17A1 Antibody is a Rabbit Polyclonal antibody against CYP17A1. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008].
Research Articles on Steroid 17-Alpha-Hydroxylase/17,20 Lyase (CYP17A1)
| Target | Steroid 17-Alpha-Hydroxylase/17,20 Lyase (CYP17A1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 209-508 of human CYP17A1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P05093 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5TZV7 |
| UniProt Entry Name | CP17A_HUMAN |
| Gene Symbol | CYP17A1 |
| GeneID | 1586 |
| NCBI Accession | NP_000093.1 |
| KEGG | hsa:1586 |
| String | 9606.ENSP00000358903 |
| Molecular Weight | Calculated MW: 57 kDa Observed MW: 57 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |