+44 (0) 1223 755950
+1 832 327 7413
Cytochrome P450 1A1 (CYP1A1) Antibody
REQUEST MORE INFO
Catalogue No: abx025529
Price:
US$326.25
(Size: 80 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.
Research Articles on Cytochrome P450 1A1 (CYP1A1)
| Target | Cytochrome P450 1A1 (CYP1A1) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 377-405 amino acids from the C-terminal region of human CYP1A1. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P04798 (UniProt, ExPASy) |
| UniProt Secondary AC | A4F3V9, A4F3W0, Q53G18 |
| UniProt Entry Name | CP1A1_HUMAN |
| KEGG | hsa:1543 |
| String | 9606.ENSP00000369050 |
| Molecular Weight | Calculated MW: 58.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Monkey CYP1A1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |