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Cytochrome P450 1A2 (CYP1A2) Antibody
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Catalogue No: abx025440
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.
Research Articles on Cytochrome P450 1A2 (CYP1A2)
| Target | Cytochrome P450 1A2 (CYP1A2) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 255-282 amino acids from human CYP1A2. |
| Isotype | IgG3 |
| Form | Liquid |
| Purification | Purified Mouse Monoclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P05177 (UniProt, ExPASy) |
| UniProt Secondary AC | Q16754, Q6NWU3, Q6NWU5, Q9BXX7, Q9UK49 |
| UniProt Entry Name | CP1A2_HUMAN |
| KEGG | hsa:1544 |
| String | 9606.ENSP00000342007 |
| Molecular Weight | Calculated MW: 58.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |