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Cytochrome P450 2C9 (CYP2C9) Antibody
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Catalogue No: abx025527
Price:
US$601.75
(Size: 100 µl)
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. This antibody is supplied as crude ascites.
Research Articles on Cytochrome P450 2C9 (CYP2C9)
| Target | Cytochrome P450 2C9 (CYP2C9) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/100 - 1/1600. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 82-110 amino acids from the N-terminal region of human CYP2C9. |
| Isotype | IgM |
| Form | Liquid |
| Purification | Unpurified crude ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P11712 (UniProt, ExPASy) |
| UniProt Secondary AC | P11713, Q16756, Q16872, Q5VX92, Q6IRV8, Q8WW80 |
| Gene Symbol | CYP2C9 |
| GeneID | 1559 |
| OMIM | 601130 |
| HGNC | 2623 |
| KEGG | hsa:1559 |
| Ensembl | ENSG00000138109 |
| String | 9606.ENSP00000260682 |
| Molecular Weight | Calculated MW: 55.6 kDa |
| Buffer | Ascites containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |