Cytochrome P450 3A5 (CYP3A5) Antibody

CYP3A5 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione.

Target	Cytochrome P450 3A5 (CYP3A5)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 186-218 amino acids from the Central region of human CYP3A5.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P20815 (UniProt, ExPASy)
UniProt Secondary AC	A4D289, B7Z5I7, Q53WY8, Q75MV0, Q9HB56
UniProt Entry Name	CP3A5_HUMAN
KEGG	hsa:1577
String	9606.ENSP00000222982
Molecular Weight	Calculated MW: 57.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cytochrome P450 3A5 (CYP3A5)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue