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Cytochrome P450 3A5 (CYP3A5) Antibody
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Catalogue No: abx033686
Price:
US$326.25
(Size: 80 µl)
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CYP3A5 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione.
Research Articles on Cytochrome P450 3A5 (CYP3A5)
| Target | Cytochrome P450 3A5 (CYP3A5) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 476-502 amino acids from the C-terminal region of human CYP3A5. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P20815 (UniProt, ExPASy) |
| UniProt Secondary AC | A4D289, B7Z5I7, Q53WY8, Q75MV0, Q9HB56 |
| UniProt Entry Name | CP3A5_HUMAN |
| KEGG | hsa:1577 |
| String | 9606.ENSP00000222982 |
| Molecular Weight | Calculated MW: 57.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |