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Lanosterol 14-Alpha Demethylase (CYP51A1) Antibody
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Catalogue No: abx034137
Price:
US$326.25
(Size: 80 µl)
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CYP51A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol.
Research Articles on Lanosterol 14-Alpha Demethylase (CYP51A1)
| Target | Lanosterol 14-Alpha Demethylase (CYP51A1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 474-503 amino acids from the C-terminal region of human CYP51A1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q16850 (UniProt, ExPASy) |
| UniProt Entry Name | CP51A_HUMAN |
| KEGG | hsa:1595 |
| String | 9606.ENSP00000003100 |
| Molecular Weight | Calculated MW: 57.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Pig and Monkey CYP51A1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |