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Lanosterol 14-Alpha Demethylase (CYP51A1) Antibody
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Catalogue No: abx004774
Price:
US$217.50
(Size: 20 µl)
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CYP51A1 Antibody is a Rabbit Polyclonal antibody against CYP51A1. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on Lanosterol 14-Alpha Demethylase (CYP51A1)
| Target | Lanosterol 14-Alpha Demethylase (CYP51A1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 210-509 of CYP51A1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q16850 (UniProt, ExPASy) |
| UniProt Entry Name | CP51A_HUMAN |
| Gene Symbol | CYP51A1 |
| GeneID | 1595 |
| NCBI Accession | NP_000777.1 |
| KEGG | hsa:1595 |
| String | 9606.ENSP00000003100 |
| Molecular Weight | Calculated MW: 57 kDa Observed MW: 57 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 3.52 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |