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Cytochrome P450 24A1 (CYP24A1) Antibody
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Catalogue No: abx147628
Price:
US$406.00
(Size: 100 µg)
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Cytochrome P450 24A1 (CYP24A1) Antibody is a Rabbit Polyclonal antibody for the detection of CYP24A1. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1, 25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Articles on Cytochrome P450 24A1 (CYP24A1)
| Target | Cytochrome P450 24A1 (CYP24A1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | cytochrome P450, family 24, subfamily A, polypeptide 1 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | Q07973 (UniProt, ExPASy) |
| UniProt Secondary AC | Q15807, Q32ML3, Q5I2W7 |
| UniProt Entry Name | CP24A_HUMAN |
| Gene Symbol | CYP24A1 |
| GeneID | 1591 |
| OMIM | 126065 |
| HGNC | 2602 |
| KEGG | hsa:1591 |
| Ensembl | ENSG00000019186 |
| String | 9606.ENSP00000216862 |
| Molecular Weight | Observed MW: 43 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |