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Defender Against Cell Death 1 (DAD1) Antibody
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Catalogue No: abx029525
Price:
US$290.00
(Size: 80 µl)
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DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes. [provided by RefSeq].
Research Articles on Defender Against Cell Death 1 (DAD1)
| Target | Defender Against Cell Death 1 (DAD1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 64-92 amino acids from the C-terminal region of human DAD1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P61803 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DS25, O08552, O70364, P46966, P46968, Q6FGA3, Q96GB7 |
| UniProt Entry Name | DAD1_HUMAN |
| KEGG | hsa:1603 |
| String | 9606.ENSP00000250498 |
| Molecular Weight | Calculated MW: 12.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow and Pig DAD1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |