Drebrin (DBN1) Antibody

DBN1 Antibody is a Rabbit Polyclonal antibody against DBN1. The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.

Target	Drebrin (DBN1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 350-649 of human DBN1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q16643 (UniProt, ExPASy)
UniProt Secondary AC	A8MV58, B2RBG0, Q9UFZ5
UniProt Entry Name	DREB_HUMAN
Gene Symbol	DBN1
GeneID	1627
NCBI Accession	NP_004386.2
KEGG	hsa:1627
String	9606.ENSP00000292385
Molecular Weight	Calculated MW: 71 kDa Observed MW: 110 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Drebrin (DBN1)

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