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Deoxycytidine Kinase (DCK) Antibody
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Catalogue No: abx001486
Price:
US$217.50
(Size: 20 µl)
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DCK Antibody is a Rabbit Polyclonal antibody against DCK. Deoxycytidine kinase (dCK) is required for the phosphorylation of several deoxyribonucleoside analogues that are widely employed as chemotherapeutic agents(PMID:12628850). It is also a key enzyme in the phosphorylation of a variety of antineoplastic and antiviral nucleoside analogs including cytosine arabinoside (araC) and dideoxycytidine (ddCyd); deficiency of deoxycytidine kinase activity mediates resistance to these drugs(PMID:1996353). This protein can exsit as a homodimer(PMID:16421443). This antibody is specific to DCK.
Research Articles on Deoxycytidine Kinase (DCK)
| Target | Deoxycytidine Kinase (DCK) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/1000 - 1/5000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DCK. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P27707 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R8V6, Q5TZY7, Q6FI11 |
| UniProt Entry Name | DCK_HUMAN |
| Gene Symbol | DCK |
| GeneID | 1633 |
| NCBI Accession | NP_000779.1 |
| KEGG | hsa:1633 |
| String | 9606.ENSP00000286648 |
| Molecular Weight | Calculated MW: 31 kDa Observed MW: 31 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |