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M7GpppX Diphosphatase (DCPS) Antibody
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Catalogue No: abx029282
Price:
US$326.25
(Size: 80 µl)
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Necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA fragments shorter than 10 nucleotides that are produced by 3'->5' exosome-mediated mRNA decay. Releases m7GMP. Can also degrade m7GDP to m7GMP. Has no activity towards mRNA molecules longer than 25 nucleotides.
Research Articles on M7GpppX Diphosphatase (DCPS)
| Target | M7GpppX Diphosphatase (DCPS) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 165-193 amino acids from the Central region of human DCPS. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q96C86 (UniProt, ExPASy) |
| UniProt Secondary AC | Q8NHL8, Q9Y2S5 |
| UniProt Entry Name | DCPS_HUMAN |
| Gene Symbol | DCPS |
| GeneID | 28960 |
| OMIM | 610534 |
| HGNC | 29812 |
| KEGG | hsa:28960 |
| Ensembl | ENSG00000110063 |
| String | 9606.ENSP00000263579 |
| Molecular Weight | Calculated MW: 38.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow and Pig DCPS. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |