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Dynactin Subunit 2 (DCTN2) Antibody
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Catalogue No: abx027082
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.
Research Articles on Dynactin Subunit 2 (DCTN2)
| Target | Dynactin Subunit 2 (DCTN2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 192-219 amino acids from the Central region of human DCTN2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13561 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RBK5, Q86YN2, Q9BW17 |
| UniProt Entry Name | DCTN2_HUMAN |
| KEGG | hsa:10540 |
| String | 9606.ENSP00000408910 |
| Molecular Weight | Calculated MW: 44.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat and Cow DCTN2. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |