DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 17 (DDX17) Antibody

DDX17 box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This protein encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family.

Target	DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 17 (DDX17)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 128-155 amino acids from the N-terminal region of human DDX17.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q92841 (UniProt, ExPASy)
UniProt Secondary AC	B1AHM0, H3BLZ8, Q69YT1, Q6ICD6
UniProt Entry Name	DDX17_HUMAN
KEGG	hsa:10521
String	9606.ENSP00000380033
Molecular Weight	Calculated MW: 80.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse DDX17.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 17 (DDX17)

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