DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21) Antibody

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.

Target	DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 128-156 amino acids from the N-terminal region of human DDX21.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9NR30 (UniProt, ExPASy)
UniProt Secondary AC	B2RDL0, Q13436, Q5VX41, Q68D35
UniProt Entry Name	DDX21_HUMAN
Gene Symbol	DDX21
String	9606.ENSP00000346120
Molecular Weight	Calculated MW: 87.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21)

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