DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 23 (DDX23) Antibody

DDX23 encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing.

Target	DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 23 (DDX23)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 248-277 amino acids from the Central region of human DDX23.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9BUQ8 (UniProt, ExPASy)
UniProt Secondary AC	B2R600, B4DH15, O43188
UniProt Entry Name	DDX23_HUMAN
Gene Symbol	DDX23
String	9606.ENSP00000310723
Molecular Weight	Calculated MW: 95.6 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 23 (DDX23)

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