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Death Effector Domain Containing (DEDD) Antibody
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Catalogue No: abx004448
Price:
US$217.50
(Size: 20 µl)
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DEDD Antibody is a Rabbit Polyclonal antibody against DEDD. This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.
Research Articles on Death Effector Domain Containing (DEDD)
| Target | Death Effector Domain Containing (DEDD) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-318 of human DEDD. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O75618 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DVF5, O60737 |
| UniProt Entry Name | DEDD_HUMAN |
| Gene Symbol | DEDD |
| GeneID | 9191 |
| NCBI Accession | NP_001034801.1 |
| KEGG | hsa:9191 |
| String | 9606.ENSP00000356985 |
| Molecular Weight | Calculated MW: 37 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |