DEFB132 Antibody is a Rabbit Polyclonal antibody against DEFB132. ∫-defensins (also designated BDs, or hBDs in human) are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, ∫-defensins are developmentally regulated. The family of ∫-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many ∫-defensins also are involved in sperm maturation and capacitation. ∫-defensin 32, also known as ∫-defensin 132, is a 95 amino acid secreted protein that most likely contains a signal peptide sequence that requires cleavage by proteolytic enzymes in order to become biologically active.

Target	Beta-Defensin 132 (DEFB132)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	IHC
Host	Rabbit
Recommended dilutions	IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein corresponding to human DEFB132
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q7Z7B7 (UniProt, ExPASy)
UniProt Secondary AC	B2RP72, Q4QY40
UniProt Entry Name	DB132_HUMAN
Gene Symbol	DEFB132
GeneID	400830
NCBI Accession	NP_997352.1
KEGG	hsa:400830
String	9606.ENSP00000371813
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Research Articles on Beta-Defensin 132 (DEFB132)

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