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Derlin-2 (DERL2) Antibody
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Catalogue No: abx030935
Price:
US$290.00
(Size: 80 µl)
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Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate (By similarity).
Research Articles on Derlin-2 (DERL2)
| Target | Derlin-2 (DERL2) |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 191-219 amino acids from the C-terminal region of mouse Derl2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q8BNI4 (UniProt, ExPASy) |
| UniProt Secondary AC | Q920I5, Q99J12 |
| UniProt Entry Name | DERL2_MOUSE |
| KEGG | mmu:116891 |
| String | 10090.ENSMUSP00000117052 |
| Molecular Weight | Calculated MW: 27.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |